Prop WP Nel has been ruled out of Scotland's Six Nations campaign with a neck injury.
Eddie Jones has included three uncapped players in England's 34-man squad for the upcoming Six Nations tournament.
Uncapped flank Cornell du Preez is one of four South African-born players in Scotland's 37-man squad for the forthcoming Six Nations.
South African-born Scott Spedding has been included in France's 32-man Six Nations squad.
Lock Alun-Wyn Jones has replaced Sam Warburton as captain in Wales' 36-man squad for the 2017 Six Nations tournament.
Ireland hooker Sean Cronin has been ruled out of the Six Nations after sustaining a hamstring injury.
Joe Marler will miss the first half of the Six Nations after suffering a lower leg fracture.
England flank Chris Robshaw will undergo surgery on his left shoulder on Monday that will sideline him for 12 weeks.
England coach Eddie Jones says the introduction of bonus points in the Six Nations will not change the way teams play.
Scotland v Ireland
England v France
Italy v Wales
Italy v Ireland
The make-up of the South African squads that will compete in the Africa 1 and Africa 2 conferences in 2017.
The make-up of the squads that will compete in the New Zealand conference in 2017.
The make-up of the squads that will compete in the Australian conference in 2017.
The Stormers have suffered an injury blow ahead of Super Rugby after new signing Steph de Wit broke his ankle in training on Tuesday.
Saracens ground out a 10-3 victory over Toulon in the European Champions Cup, to secure a home quarter-final.View all videos