Damian de Allende will make his first start of the season for the Stormers against the Reds at Newlands on Saturday.
The Springbok will partner Johnny Kotze in midfield after co-captain Juan de Jongh was ruled out due to a delayed concussion.
Meanwhile, Frans Malherbe returns to the starting XV to lead the side in one of four rotational changes to the pack.
He is joined by Oli Kebble in the front row, with Vincent Koch and JC Janse van Rensburg named on the replacements bench.
Rynhardt Elstadt makes his first start of the season at lock, with JD Schickerling on the bench, while in the loose trio Schalk Burger makes way for Siya Kolisi, with Nizaam Carr moving to No 8.
Stormers – 15 Cheslin Kolbe, 14 Kobus van Wyk, 13 Johnny Kotze, 12 Damian de Allende, 11 Leolin Zas, 10 Jean-Luc du Plessis, 9 Nic Groom, 8 Nizaam Carr, 7 Siya Kolisi, 6 Sikhumbuzo Notshe, 5 Pieter-Steph du Toit, 4 Rynhardt Elstadt, 3 Frans Malherbe (c), 2 Bongi Mbonambi, 1 Oli Kebble.
Subs: 16 Mike Willemse, 17 JC Janse van Rensburg, 18 Vincent Koch, 19 JD Schickerling, 20 Schalk Burger, 21 Louis Schreuder, 22 Huw Jones, 23 Brandon Thomson.
Photo: Carl Fourie/Gallo Images