Ellis Jenkins will captain a largely second-string Wales team against Tonga in Cardiff on Saturday.
Former Highlanders captain and current Tonga international Nasi Manu will undergo chemotherapy after he was diagnosed with a form of urological cancer.
Tonga exploited a yellow card to score a try and snatch a 27-19 win against Fiji in Suva on Saturday.
Sonatane Takulua kicked 13 points as Tonga clinched a 28-18 win over Samoa in Suva on Saturday.
Fullback Ioseb Matiashvilli scored all of Georgia’s points as they claimed a 16-15 victory over Tonga in the Pacific Nations Cup in Fiji on Saturday.
Lomano Lemeki scored a brace of tries as Japan cruised to a 39-6 victory against Tonga in Toulouse on Saturday.
Robert du Preez scored seven crucial points as the Barbarians beat Tonga 27-24 at Thomond Park in Limerick.