Table-topping Tuks will be looking for their first away win of the Varsity Cup when they travel to Potchefstroom to face Pukke on Monday.
The hosts scored seven tries to claim a comprehensive 53-8 win in Pretoria.
The visitors scored nine tries to win 57-0 in Bloemfontein.
Tuks romped to a 53-8 victory over Maties in their third round Varsity Cup match in Pretoria on Monday.
Maties flank Beyers de Villiers is expecting an early physical onslaught from Tuks in Pretoria on Monday night.
Tuks will host Maties in the big north-south Varsity Cup showdown on Monday night.
Former Springbok coach Peter de Villiers says he is being blocked 'everywhere I go' in South Africa.
Maties scored a late try to draw 26-26 with Pukke in their second round Varsity Cup clash in Stellenbosch on Monday.
Fullback Rhyno Smith is hoping to produce another good performance when Pukke take on Maties in Stellenbosch on Monday.
Maties will host last year's finalists Pukke in round two of the Varsity Cup on Monday with champions UCT travelling to Tuks.