UKZN shocked Wits 29-24 in Johannesburg on Monday to claim their first Varsity Shield title.
Wits will go into Monday's decider against UKZN in Johannesburg as favourites.
Last year's Varsity Cup finalists beat this year's table-toppers 29-28 in Pretoria.
The hosts knocked the defending Varsity Cup champions out with a 21-10 win in Bloemfontein.
Shimlas and Pukke will contest the 2015 Varsity Cup final after securing semi-final wins over UCT and Tuks on Monday.
Both of last year's finalists will play away from home in the Varsity Cup semi-finals on Monday.
The Varsity Cup semi-finals and final will see the traditional rugby posts replaced with American football-style posts.
The hosts won 29-26 in Bloemfontein, with the visitors' doing just enough to qualify for the semi-finals.
The Pretoria students won 40-8 in PE to finish top of the Varsity Cup log.