Xavier Chiocci will make his first start in one of five changes to the French side to face Argentina in Paris on Saturday.
Chiocci comes in for Alexandré Menini at loosehead, with Benjamin Kayser replacing Guilhem Guirado at hooker and Sébastien Vahaamahina starting ahead of Yoann Maestri at No 5 lock.
Among the backs, Maxime Mermoz replaces Alexandre Dumoulin at outside centre, while Maxime Médard will wear the No 11 jersey after Teddy Thomas was dropped for missing training.
France have won both of their November internationals so far, comfortably beating Fiji in Marseille, before gaining revenge for a 3-0 whitewash in the June Tests against the Wallabies in Paris a week later.
Coach Philippe Saint-André has yet to name his eight-man bench.
France – 15 Scott Spedding, 14 Yoann Huget, 13 Maxime Mermoz, 12 Wesley Fofana, 11 Maxime Médard, 10 Camille Lopez, 9 Sébastien Tillous-Borde, 8 Damien Chouly, 7 Bernard Le Roux, 6 Thierry Dusautoir (c), 5 Sébastien Vahaamahina, 4 Pascal Papé, 3 Nicolas Mas, 2 Benjamin Kayser, 1 Xavier Chiocci.
Subs (from): Alexandre Menini, Guilhem Guirado, Uini Atonio, Alexandre Flanquart, Yoann Maestri, Yannick Nyanga, Charles Ollivon, Rory Kockott, Rémi Talès, Mathieu Bastareaud, Benjamin Fall.
Photo: Lionel Bonaventure/AFP Photo