Tomos Williams will make his Six Nations debut after being named as the starting scrumhalf in Wales’ lineup to face France in Paris on Friday.
Williams will be alongside Cardiff Blues teammate Gareth Anscombe, who has been given the No 10 jersey.
Scarlets duo Hadleigh Parkes and Jonathan Davies continue their partnership in midfield, with Josh Adams, George North and Liam Williams comprising the back three.
Captain Alun Wyn Jones and Adam Beard are in the second row, with Josh Navidi returning from injury to start in the back row alongside British & Irish Lions Justin Tipuric and Ross Moriarty.
In the front row, Rob Evans and Tomas Francis pack down alongside Ken Owens, who becomes Wales’ most capped hooker, making his 61st appearance for his country.
Wales – 15 Liam Williams; 14 George North, 13 Jonathan Davies, 12 Hadleigh Parkes, 11 Josh Adams; 10 Gareth Anscombe, 9 Tomos Williams, 8 Ross Moriarty, 7 Justin Tipuric, 6 Josh Navidi, 5 Alun Wyn Jones (c), 4 Adam Beard, 3 Tomas Francis, 2 Ken Owens, 1 Rob Evans.
Subs: 16 Elliot Dee, 17 Wyn Jones, 18 Samson Lee, 19 Cory Hill, 20 Aaron Wainwright, 21 Gareth Davies, 22 Dan Biggar, 23 Owen Watkin.
Photo: Michael Steele/Getty Images